CorMedix stock price drops 5% due to Q4 earnings falling short of expectations

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New Jersey Parsippany - On Thursday, CorMedix Inc. (NASDAQ: CRMD) announced its Q4 earnings, which fell short of profit expectations despite meeting revenue targets.

The company’s stock dropped 5.34% in pre-market trading.

The biopharmaceutical company’s adjusted earnings per share for the quarter were $0.16, significantly below the analyst consensus of $0.85.

Revenue reached $128.6 million, slightly above the expected $128.48 million, representing a substantial increase from $31.2 million in the same period last year.

The 312% year-over-year revenue growth was primarily driven by DefenCath sales of $91.2 million and Melinta product portfolio sales of $37.4 million, following the company’s acquisition of Melinta in August 2025.

For the full year 2025, CorMedix reported a net profit of $163.0 million, or $2.04 per diluted share, compared to a net loss of $17.9 million in 2024.

Total annual revenue reached $311.7 million, with projected full-year revenue including Melinta’s performance at $401.3 million.

Chairman and CEO Joe Todisco stated, “I am proud of the progress we made over the past year. We accelerated patient access to DefenCath, completed the acquisition and integration of Melinta, and made progress in two ongoing Phase 3 clinical trials.”

Total operating expenses for Q4 were $48.2 million, up 182% from $17.1 million in the same period last year, mainly due to the Melinta acquisition.

The quarter included $4.1 million in one-time integration-related costs. Adjusted EBITDA for Q4 was $77.2 million, compared to $15.3 million in the same period last year.

CorMedix reaffirmed its 2026 guidance, expecting net revenue between $300 million and $320 million, with a midpoint of $310 million, and adjusted EBITDA between $100 million and $125 million. The company expects to release Phase 3 ReSPECT study data for REZZAYO in Q2 2026.

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