Alnylam and Tenaya sign $1.23bn cardiovascular target discovery deal

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Alnylam Pharmaceuticals has partnered with Tenaya Therapeutics in a deal worth up to $1.23 billion to discover novel genetic targets for heart disease. Alnylam will pay an upfront fee of $10 million and up to $1.13 billion in milestone payments for drugs developed from these targets. This collaboration aims to expand Alnylam’s presence in the cardiovascular market, building on the success of its ATTR-CM therapy, Amvuttra.

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